DIRECTORS

Simon Gayther, PhD

Dr. Gayther’s research program is largely focused on understanding the underlying causes of ovarian cancer initiation and development. Dr Gayther has a long established track record in defining the heritable component of ovarian cancer, and the functional role of both common and rare risk variants and their target susceptibility genes in the early stage disease pathogenesis.The overall approach of this research program is to integrate genomics and epigenomics analyses to identify molecular markers associated with disease, with cell biology modeling studies to validate the role of novel molecular markers in disease biology. 

Simon Knott, PhD

Simon received his PhD from the Department of Molecular and Computational Biology at the University of Southern California, with Dr. Oscar Aparicio and Dr. Simon Tavaré acting as his mentors. Subsequently, he joined the laboratory of Dr. Gregory Hannon at Cold Spring Harbor Laboratory. In the Hannon lab, he developed computational and molecular tools to study gene function in mammalian cells. In addition, he applied these tools to identify novel drivers of breast cancer progression.

ASSOCIATE DIRECTOR

Jasmine Plummer, PhD

Dr. Plummer completed her HonBSc in Biology and Chemistry at University of Toronto, Toronto, Canada where she worked with Dr. JJB Smith on sensory circuitry.Dr. Plummer joined the Department of Physiology and Biophysics, at Dalhousie University (Halifax, Canada) in the laboratory of Dr. Croll. She completed her Masters of Science (MSc) in neuroscience, specializing in comparative neurobiology and neuro development.  In her PhD work,, Dr.Plummer took a genetic approach to identifying new genes that regulate the development of the nervous system. Dr. Plummer’s post-doctoral fellowship focused on systems biology approaches to understanding genetic risk of neurodevelopmental disorders.