Our goal is to generate genomic, transcriptomic, epigenomic & metagenomic information for basic and clinical research. Our mission is to make complex technologies and methodologies available and interpretable to the research community.

EVENTS

BFG/GENOMICS SEMINAR SERIES

08.04.2020

Genomics Analysis in COVID-19 Cases

Jasmine Plummer, PhD

Associate Director, AGCT Core

Tuesday, August 4, 2020 10am-11am

Via WebEx

NEWS

CONGRATULATIONS SIMON KNOTT 

ON DOD AWARD! 

04.17.2019

Simon Knott's Breast Cancer Research Program (BCRP) Breakthrough Award -Funding Level 3- Clinical Trial - Partnering PI Options application was recommended for funding by the Department of Defense. 

Grant titled "Overcoming Immunotherapy Resistance in Breast Cancer Using RT-Mediated Immunomodulation" for funding. Congrats!

CENTER FOR BIOINFORMATICS AND FUNCTIONAL GENOMICS

09.10.2018

The Genomics Core and the Center for Bioinformatics and Functional Genomics (BFG) have joined forces to bring you the Applied Genomics Computation & Translational (AGCT) Core.  Together, we make complex technologies accessible and biologically interpretable for clinical and basic research scientists.

  • Twitter

10X GENOMICS CERTIFIED

06.10.2018

The Genomics Core achieved the distinction of a 10x Genomics Certified Service Provider in Single Cell Gene Expression.  We are the sole service provider on the west coast. 

Contact us at for price inquiries.

NEW SERVICES

06.07.2018

The Genomics Core is pleased to announce the addition of 3 new services:

•Omni-ATAC-Seq: an improved ATAC-seq protocol for chromatin accessibility profiling that works across multiple applications with substantial improvement of signal-to-background ratio and information content

•CITE-Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing): simultaneous profiling of single cell transcriptomes and cell surface proteins

•Cell hashing/sample multiplexing: sample-specific tagging of individual cells for multiplexing of samples for single cell RNA-Seq

LATEST PAPERS + STUDIES

Gusev A, Lawrenson K, Lin X, Lyra Jr. PC, Kar S, Vavra K, 

Segato F, Fonseca MAS, Lee J, Pejovic T, Liu G, Ovarian Cancer Association ConsortiumKarlan BY, Freedman ML, 

Noushmehr H, Monteiro A, Pharoah P, Pasaniuc B, Gayther SA. A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nature Genetics. May 2019    PDF

Skalski JH, Limon-Tello JJ, Sharma P, Gargus MD, Ngyuen C, Tang J, Coelho AL, Hogaboam CM, Crother TR, Underhill DM. Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice. PLOS Pathogens. 2018      PDF

Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D.Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 2018    PDF

Ljubimova JY, Braubach O, Patil R, Chiechi A, Tang J, Galstyan A, Shatalova ES, Kleinman MT, Black KL, Holler E. Coarse particulate matter (PM2.5-10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains. Sci Rep. 2018     PDF

Contact Us

8723 Alden Dr. 
Steven Spielberg Building
Los Angeles, CA 90048

genomics@cshs.org

310-423-4066